A disease called "Gibia" has infected the world, turning people into various types of monsters, and a ninja and samurai from Japan's Edo Period have traveled through time to stop it.
In 2030, Japan. A virus has infected humans throughout the world. Infected people turn into different forms of monsters based on their ages, sexes and races. The virus is named 'Gibia' - after being rich in variety like gibia. Just then, a pair of samurai and ninja appeared in such a blighted wasteland of Japan. They both traveled from the early Edo period, fighting together with help from a doctor who tries to find cure for Gibia. Facing ceaseless attacks from Gibias, and outlaws that attack travelers for food, they start the dangerous journey with enemies all around.

ซามูไร นินจา และพระเดินทางข้ามเวลาจากยุคเอโดะไปยังปี 2030 เพื่อช่วยศาสตราจารย์คนหนึ่งหาวิธีรักษาเชื้อไวรัสที่เปลี่ยนมนุษย์ให้กลายเป็นอสุรกาย